Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN

Maternally expressed gene 3 (MEG3) encodes an lncRNA which is suggested to function as a tumor suppressor and has been showed to involve in a variety of cancers. Herein, our findings demonstrate that MEG3 inhibits the malignant progression of liver cancer cells in vitro and in vivo. Mechanistically,...

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Detalles Bibliográficos
Autores principales: Zheng, Qidi, Lin, Zhuojia, Xu, Jie, Lu, Yanan, Meng, Qiuyu, Wang, Chen, Yang, Yuxin, Xin, Xiaoru, Li, Xiaonan, Pu, Hu, Gui, Xin, Li, Tianming, Xiong, Wujun, Lu, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833746/
https://www.ncbi.nlm.nih.gov/pubmed/29449541
http://dx.doi.org/10.1038/s41419-018-0305-7

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