Reversine, a substituted purine, exerts an inhibitive effect on human renal carcinoma cells via induction of cell apoptosis and polyploidy

BACKGROUND: Human renal cell carcinoma (RCC) is the most common type of kidney cancer that arises from the renal epithelium. Up to 33.3% of RCC patients treated with local tumor resections will subsequently develop recurrence or metastases. Thus, optimized therapeutic regimes are urgently needed to...

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Detalles Bibliográficos
Autores principales: Cheng, Li, Wang, Hao, Guo, Kecun, Wang, Zicheng, Zhang, Zhongyuan, Shen, Cheng, Chen, Liang, Lin, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833753/
https://www.ncbi.nlm.nih.gov/pubmed/29520153
http://dx.doi.org/10.2147/OTT.S158198

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