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Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip

Studies on human intestinal injury induced by acute exposure to γ-radiation commonly rely on use of animal models because culture systems do not faithfully mimic human intestinal physiology. Here we used a human Gut-on-a-Chip (Gut Chip) microfluidic device lined by human intestinal epithelial cells...

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Detalles Bibliográficos
Autores principales: Jalili-Firoozinezhad, Sasan, Prantil-Baun, Rachelle, Jiang, Amanda, Potla, Ratnakar, Mammoto, Tadanori, Weaver, James C., Ferrante, Thomas C., Kim, Hyun Jung, Cabral, Joaquim M. S., Levy, Oren, Ingber, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833800/
https://www.ncbi.nlm.nih.gov/pubmed/29445080
http://dx.doi.org/10.1038/s41419-018-0304-8