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Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in elderly people. AMD is classified as early, intermediate, advanced non-neovascular, and advanced neovascular forms depending on the clinical features. However, the exact pathogenesis remains unclear. Retinal p...
Autores principales: | Wang, Jing, Feng, Yiji, Han, Peng, Wang, Fenghua, Luo, Xueting, Liang, Jian, Sun, Xiangjun, Ye, Jing, Lu, Yiming, Sun, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833825/ https://www.ncbi.nlm.nih.gov/pubmed/29415988 http://dx.doi.org/10.1038/s41419-017-0200-7 |
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