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Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence

Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in elderly people. AMD is classified as early, intermediate, advanced non-neovascular, and advanced neovascular forms depending on the clinical features. However, the exact pathogenesis remains unclear. Retinal p...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Feng, Yiji, Han, Peng, Wang, Fenghua, Luo, Xueting, Liang, Jian, Sun, Xiangjun, Ye, Jing, Lu, Yiming, Sun, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833825/
https://www.ncbi.nlm.nih.gov/pubmed/29415988
http://dx.doi.org/10.1038/s41419-017-0200-7

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