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U-box ubiquitin ligase PPIL2 suppresses breast cancer invasion and metastasis by altering cell morphology and promoting SNAI1 ubiquitination and degradation

Metastasis is the leading cause of breast cancer fatalities. To develop new therapeutic strategies, the mechanisms underlying breast cancer invasion and metastasis need to be further investigated. Peptidylprolyl isomerase (cyclophilin)-like 2 (PPIL2) is a U-box-type E3 ubiquitin ligase belonging to...

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Detalles Bibliográficos
Autores principales:	Jia, Zhaojun, Wang, Miao, Li, Shujing, Li, Xiahui, Bai, Xiao-Yan, Xu, Zhaowei, Yang, Yangyang, Li, Bowen, Li, Yanan, Wu, Huijian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833831/ https://www.ncbi.nlm.nih.gov/pubmed/29352246 http://dx.doi.org/10.1038/s41419-017-0094-4

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