PHB2 interacts with LC3 and SQSTM1 is required for bile acids-induced mitophagy in cholestatic liver

Mitophagy is a major pathway for clearance of injured mitochondria. However, whether mitophagy is involved in the cholestasis-induced damages of hepatic mitochondria remains unknown. We here aimed to investigate the molecular links between cholestasis and hepatic mitophagy. We show that mitophagy is...

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Detalles Bibliográficos
Autores principales: Xiao, Yongtao, Zhou, Ying, Lu, Ying, Zhou, Kejun, Cai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833850/
https://www.ncbi.nlm.nih.gov/pubmed/29416008
http://dx.doi.org/10.1038/s41419-017-0228-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833850/
https://www.ncbi.nlm.nih.gov/pubmed/29416008
http://dx.doi.org/10.1038/s41419-017-0228-8

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