Cargando…

miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg)

Thymic-derived regulatory T cell (tTreg) clinical trials show therapeutic promise in the prevention of acute graft-versus-host disease (GVHD) in allogeneic hematopoietic stem cell transplantation patients. However, strategies are needed to improve tTreg proliferative ability and survival as a means...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Yunjie, Gao, Ji, Zhang, Shaopeng, Gu, Jian, Lu, Hao, Xia, Yongxiang, Zhu, Qin, Qian, Xiaofeng, Zhang, Feng, Zhang, Chuanyong, shen, Hongbing, Hippen, Keli L., Blazar, Bruce R., Lu, Ling, Wang, Xuehao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833855/ https://www.ncbi.nlm.nih.gov/pubmed/29459719 http://dx.doi.org/10.1038/s41419-018-0298-2

Ejemplares similares

Capacity of tTreg generation is not impaired in the atrophied thymus
por: Oh, Jiyoung, et al.
Publicado: (2017)

Foxp3 Instability Helps tTregs Distinguish Self and Non-self
por: Zhang, Zhongmei, et al.
Publicado: (2019)

Rapamycin Regulates iTreg Function through CD39 and Runx1 Pathways
por: Lu, Yunjie, et al.
Publicado: (2014)

PU.1/microRNA-142-3p targets ATG5/ATG16L1 to inactivate autophagy and sensitize hepatocellular carcinoma cells to sorafenib
por: Zhang, Kai, et al.
Publicado: (2018)

Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
por: Brinkman, C. Colin, et al.
Publicado: (2016)

A Novel Model on DST-Induced Transplantation Tolerance by the Transfer of Self-Specific Donor tTregs to a Haplotype-Matched Organ Recipient
por: Mohr Gregoriussen, Angelica Maria, et al.
Publicado: (2017)

Blockade of miR-142-3p promotes anti-apoptotic and suppressive function by inducing KDM6A-mediated H3K27me3 demethylation in induced regulatory T cells
por: Gao, Ji, et al.
Publicado: (2019)

Human CD39(hi) regulatory T cells present stronger stability and function under inflammatory conditions
por: Gu, Jian, et al.
Publicado: (2017)

Emerging translational strategies and challenges for enhancing regulatory T cell therapy for graft-versus-host disease
por: Hippen, Keli L., et al.
Publicado: (2022)

TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A
por: Sun, Yizhe, et al.
Publicado: (2017)

Obese donor mice splenocytes aggravated the pathogenesis of acute graft-versus-host disease via regulating differentiation of Tregs and CD4(+) T cell induced-type I inflammation
por: Li, Zengyao, et al.
Publicado: (2017)

Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses
por: Saxena, Vikas, et al.
Publicado: (2022)

The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions
por: Xiong, Qiuhong, et al.
Publicado: (2015)

Transient regulatory T-cell (Treg) depletion with IL-2 diphtheria toxin fusion protein enhances clearance of acute myeloid leukemia by haploidentical natural killer (NK) cells
por: Bachanova, Veronika, et al.
Publicado: (2013)

Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma
por: Hwang, Seungmin, et al.
Publicado: (2012)

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function
por: Field, Cameron S., et al.
Publicado: (2020)

Comparative Analysis of Thymic and Blood Treg in Myasthenia Gravis: Thymic Epithelial Cells Contribute to Thymic Immunoregulatory Defects
por: Truffault, Frédérique, et al.
Publicado: (2020)

The Role of ATG16 in Autophagy and The Ubiquitin Proteasome System
por: Xiong, Qiuhong, et al.
Publicado: (2018)

Oxidation of Atg3 and Atg7 mediates inhibition of autophagy
por: Frudd, Karen, et al.
Publicado: (2018)

Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease
por: Hippen, Keli L., et al.
Publicado: (2018)

Spermine Alleviates Acute Liver Injury by Inhibiting Liver-Resident Macrophage Pro-Inflammatory Response Through ATG5-Dependent Autophagy
por: Zhou, Shun, et al.
Publicado: (2018)

Adiponectin-expressing Treg facilitate T lymphocyte development in thymic nurse cell complexes
por: Zhang, Yiwei, et al.
Publicado: (2021)

Closing the loop: Three musketeers of autophagy-ATG2, ATG18a, and ATG9
por: Mishra, Divya
Publicado: (2023)

HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 translation
por: Li, Qing, et al.
Publicado: (2021)

Molecular Characterization and Functional Analysis of Three Autophagy Genes, BxATG5, BxATG9, and BxATG16, in Bursaphelenchus xylophilus
por: Liu, Hong-Bin, et al.
Publicado: (2019)

The RNA polymerase II subunit Rpb9 activates ATG1 transcription and autophagy
por: Huang, Ting, et al.
Publicado: (2022)

Adiponectin‐expressing Treg cells in experimental thymic tumor model
por: Hanamatsu, Yuki, et al.
Publicado: (2023)

Dual roles of Atg8−PE deconjugation by Atg4 in autophagy
por: Yu, Zhong-Qiu, et al.
Publicado: (2012)

Uba1 functions in Atg7- and Atg3-independent autophagy
por: Chang, Tsun-Kai, et al.
Publicado: (2013)

Atg11 tethers Atg9 vesicles to initiate selective autophagy
por: Matscheko, Nena, et al.
Publicado: (2019)

Autophagy Induction by HIV-Tat and Methamphetamine in Primary Midbrain Neuronal Cells of Tree Shrews via the mTOR Signaling and ATG5/ATG7 Pathway
por: Li, Juan, et al.
Publicado: (2018)

Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures
por: Kaiser, Stephen E., et al.
Publicado: (2012)

Mir223 restrains autophagy and promotes CNS inflammation by targeting ATG16L1
por: Li, Yan, et al.
Publicado: (2018)

ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy
por: Wible, Daric J., et al.
Publicado: (2019)

Phosphorylation of Atg31 is required for autophagy
por: Feng, Wenzhi, et al.
Publicado: (2015)

The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
por: Rao, Yijian, et al.
Publicado: (2016)

Effects of miR-103a-3p on the autophagy and apoptosis of cardiomyocytes by regulating Atg5
por: Zhang, Chenjun, et al.
Publicado: (2019)

Rice stripe virus p2 protein interacts with ATG5 and is targeted for degradation by autophagy
por: Zhang, Xiangxiang, et al.
Publicado: (2023)

Human papillomavirus 16E6/E7 activates autophagy via Atg9B and LAMP1 in cervical cancer cells
por: Tingting, Chen, et al.
Publicado: (2019)

MiR-142-3p enhances chemosensitivity of breast cancer cells and inhibits autophagy by targeting HMGB1
por: Liang, Lu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_623nm79llp4ja8gmqpol3hc8qf