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Expression of inflammasome proteins and inflammasome activation occurs in human, but not in murine keratinocytes

Inflammasomes are multimeric protein complexes that assemble upon sensing of a variety of stress factors. Their formation results in caspase-1-mediated activation and secretion of the pro-inflammatory cytokines pro-interleukin(IL)-1β and -18, which induce an inflammatory response. Inflammation is su...

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Detalles Bibliográficos
Autores principales: Sand, Jennifer, Haertel, Eric, Biedermann, Thomas, Contassot, Emmanuel, Reichmann, Ernst, French, Lars E., Werner, Sabine, Beer, Hans-Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833864/
https://www.ncbi.nlm.nih.gov/pubmed/29348630
http://dx.doi.org/10.1038/s41419-017-0009-4

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