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Expression of inflammasome proteins and inflammasome activation occurs in human, but not in murine keratinocytes
Inflammasomes are multimeric protein complexes that assemble upon sensing of a variety of stress factors. Their formation results in caspase-1-mediated activation and secretion of the pro-inflammatory cytokines pro-interleukin(IL)-1β and -18, which induce an inflammatory response. Inflammation is su...
Autores principales: | Sand, Jennifer, Haertel, Eric, Biedermann, Thomas, Contassot, Emmanuel, Reichmann, Ernst, French, Lars E., Werner, Sabine, Beer, Hans-Dietmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833864/ https://www.ncbi.nlm.nih.gov/pubmed/29348630 http://dx.doi.org/10.1038/s41419-017-0009-4 |
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