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Glutathione transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases
Glutathione transferase classical GSH conjugation activity plays a critical role in cellular detoxification against xenobiotics and noxious compounds as well as against oxidative stress. However, this feature is also exploited by cancer cells to acquire drug resistance and improve their survival. As...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833873/ https://www.ncbi.nlm.nih.gov/pubmed/29362397 http://dx.doi.org/10.1038/s41389-017-0025-3 |