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Sealing Effects on the Storage Stability of the Cyanide Antidotal Candidate, Dimethyl Trisulfide
BACKGROUND: Dimethyl trisulfide (DMTS) is a highly lipid-soluble cyanide (CN) antidote candidate molecule. In prior studies with various US FDA-approved co-solvents, surfactants, and their combinations, aqueous solutions containing 15% polysorbate 80 (Poly80) were found to effectively solubilize DMT...
Autores principales: | Kiss, Lóránd, Duke, Anna, Kovacs, Kristof, Barcza, Tibor, Kiss, Márton, Petrikovics, Ilona, Thompson, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833904/ https://www.ncbi.nlm.nih.gov/pubmed/29214385 http://dx.doi.org/10.1007/s40268-017-0220-x |
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