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P4HA1: A single-gene surrogate of hypoxia signatures in oral squamous cell carcinoma patients

BACKGROUND AND PURPOSE: Hypoxia gene expression signatures are of high prognostic value for head and neck cancer patients. Recently, the prognostic information of a multiple-gene hypoxia signature was found to be provided by the mRNA level of P4HA1 alone (Tawk et al., 2016). Therefore, we studied th...

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Detalles Bibliográficos
Autores principales: Kappler, Matthias, Kotrba, Johanna, Kaune, Tom, Bache, Matthias, Rot, Swetlana, Bethmann, Daniel, Wichmann, Henri, Güttler, Antje, Bilkenroth, Udo, Horter, Susanne, Gallwitz, Lisa, Kessler, Jacqueline, Greither, Thomas, Taubert, Helge, Eckert, Alexander W., Vordermark, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833914/
https://www.ncbi.nlm.nih.gov/pubmed/29594211
http://dx.doi.org/10.1016/j.ctro.2017.05.002