A randomized phase III study evaluating the efficacy of single-dose NEPA, a fixed antiemetic combination of netupitant and palonosetron, versus an aprepitant regimen for prevention of chemotherapy-induced nausea and vomiting (CINV) in patients receiving highly emetogenic chemotherapy (HEC)

BACKGROUND: Co-administration of multiple antiemetics that inhibit several molecular pathways involved in emesis is required to optimize chemotherapy-induced nausea and vomiting (CINV) control in patients receiving highly emetogenic chemotherapy (HEC). NEPA, a fixed combination of a highly selective...

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Detalles Bibliográficos
Autores principales: Zhang, L, Lu, S, Feng, J, Dechaphunkul, A, Chang, J, Wang, D, Chessari, S, Lanzarotti, C, Jordan, K, Aapro, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834144/
https://www.ncbi.nlm.nih.gov/pubmed/29092012
http://dx.doi.org/10.1093/annonc/mdx698

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