High content screening of patient-derived cell lines highlights the potential of non-standard chemotherapeutic agents for the treatment of glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common primary brain malignancy in adults, yet survival outcomes remain poor. First line treatment is well established, however disease invariably recurs and improving prognosis is challenging. With the aim of personalizing therapy at recurrence, we have es...

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Detalles Bibliográficos
Autores principales: Yu, Kenny Kwok-Hei, Taylor, Jessica T., Pathmanaban, Omar N., Youshani, Amir Saam, Beyit, Deniz, Dutko-Gwozdz, Joanna, Benson, Roderick, Griffiths, Gareth, Peers, Ian, Cueppens, Peter, Telfer, Brian A., Williams, Kaye J., McBain, Catherine, Kamaly-Asl, Ian D., Bigger, Brian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834163/
https://www.ncbi.nlm.nih.gov/pubmed/29499065
http://dx.doi.org/10.1371/journal.pone.0193694

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