RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes

The sex chromosomes are enriched with germline genes that are activated during the late stages of spermatogenesis. Due to meiotic sex chromosome inactivation (MSCI), these sex chromosome-linked genes must escape silencing for activation in spermatids, thereby ensuring their functions for male reprod...

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Detalles Bibliográficos
Autores principales: Adams, Shannel R., Maezawa, So, Alavattam, Kris G., Abe, Hironori, Sakashita, Akihiko, Shroder, Megan, Broering, Tyler J., Sroga Rios, Julie, Thomas, Michael A., Lin, Xinhua, Price, Carolyn M., Barski, Artem, Andreassen, Paul R., Namekawa, Satoshi H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834201/
https://www.ncbi.nlm.nih.gov/pubmed/29462142
http://dx.doi.org/10.1371/journal.pgen.1007233

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