DHX29 functions as an RNA co-sensor for MDA5-mediated EMCV-specific antiviral immunity

Melanoma differentiation-associated gene-5 (MDA5) recognizes distinct subsets of viruses including Encephalomyocarditis virus (EMCV) of picornavirus family, but the molecular mechanisms underlying the specificity of the viral recognition of MDA5 in immune cells remain obscure. DHX29 is an RNA helica...

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Detalles Bibliográficos
Autores principales: Zhu, Qingyuan, Tan, Peng, Li, Yinyin, Lin, Meng, Li, Chaoran, Mao, Jingrong, Cui, Jun, Zhao, Wei, Wang, Helen Y., Wang, Rong-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834211/
https://www.ncbi.nlm.nih.gov/pubmed/29462185
http://dx.doi.org/10.1371/journal.ppat.1006886

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