Cargando…

Discovery and validation of a glioblastoma co-expressed gene module

Tumors exhibit complex patterns of aberrant gene expression. Using a knowledge-independent, noise-reducing gene co-expression network construction software called KINC, we created multiple RNAseq-based gene co-expression networks relevant to brain and glioblastoma biology. In this report, we describ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dunwoodie, Leland J., Poehlman, William L., Ficklin, Stephen P., Feltus, Frank Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834250/ https://www.ncbi.nlm.nih.gov/pubmed/29541392 http://dx.doi.org/10.18632/oncotarget.24228

Ejemplares similares

Discovering Condition-Specific Gene Co-Expression Patterns Using Gaussian Mixture Models: A Cancer Case Study
por: Ficklin, Stephen P., et al.
Publicado: (2017)

Sorting Five Human Tumor Types Reveals Specific Biomarkers and Background Classification Genes
por: Roche, Kimberly E., et al.
Publicado: (2018)

A Systems-Genetics Approach and Data Mining Tool to Assist in the Discovery of Genes Underlying Complex Traits in Oryza sativa
por: Ficklin, Stephen P., et al.
Publicado: (2013)

Conserved Non-Coding Regulatory Signatures in Arabidopsis Co-Expressed Gene Modules
por: Spangler, Jacob B., et al.
Publicado: (2012)

Maximizing capture of gene co-expression relationships through pre-clustering of input expression samples: an Arabidopsis case study
por: Feltus, F Alex, et al.
Publicado: (2013)

Identifying Temporally Regulated Root Nodulation Biomarkers Using Time Series Gene Co-Expression Network Analysis
por: Poehlman, William L., et al.
Publicado: (2019)

OSG-GEM: Gene Expression Matrix Construction Using the Open Science Grid
por: Poehlman, William L., et al.
Publicado: (2016)

Massive-Scale Gene Co-Expression Network Construction and Robustness Testing Using Random Matrix Theory
por: Gibson, Scott M., et al.
Publicado: (2013)

Exploration into biomarker potential of region-specific brain gene co-expression networks
por: Hang, Yuqing, et al.
Publicado: (2020)

Linking Binary Gene Relationships to Drivers of Renal Cell Carcinoma Reveals Convergent Function in Alternate Tumor Progression Paths
por: Poehlman, William L., et al.
Publicado: (2019)

A Medicago truncatula Autoregulation of Nodulation Mutant Transcriptome Analysis Reveals Disruption of the SUNN Pathway Causes Constitutive Expression Changes in Some Genes, but Overall Response to Rhizobia Resembles Wild-Type, Including Induction of TML1 and TML2
por: Schnabel, Elise L., et al.
Publicado: (2023)

Large-Scale Gene Relocations following an Ancient Genome Triplication Associated with the Diversification of Core Eudicots
por: Wang, Yupeng, et al.
Publicado: (2016)

Addressing noise in co-expression network construction
por: Burns, Joshua J R, et al.
Publicado: (2021)

Identification of condition-specific regulatory mechanisms in normal and cancerous human lung tissue
por: Hang, Yuqing, et al.
Publicado: (2022)

Modes of Gene Duplication Contribute Differently to Genetic Novelty and Redundancy, but Show Parallels across Divergent Angiosperms
por: Wang, Yupeng, et al.
Publicado: (2011)

Moving Just Enough Deep Sequencing Data to Get the Job Done
por: Mills, Nicholas, et al.
Publicado: (2019)

Time Series Transcriptome Analysis in Medicago truncatula Shoot and Root Tissue During Early Nodulation
por: Gao, Yueyao, et al.
Publicado: (2022)

Discovery of eQTL Alleles Associated with Autism Spectrum Disorder: A Case–Control Study
por: Hickman, Allison R., et al.
Publicado: (2022)

Tripal v1.1: a standards-based toolkit for construction of online genetic and genomic databases
por: Sanderson, Lacey-Anne, et al.
Publicado: (2013)

RNAseq Analysis of the Response of Arabidopsis thaliana to Fractional Gravity Under Blue-Light Stimulation During Spaceflight
por: Herranz, Raúl, et al.
Publicado: (2019)

Education for Pediatric Gastroenterology Pathology Reports Increases Understanding Ahead of 21st Century Cures Act Rollout
por: Dunwoodie, Leland, et al.
Publicado: (2022)

Chromosomal characteristics of salt stress heritable gene expression in the rice genome
por: McGowan, Matthew T., et al.
Publicado: (2021)

Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma
por: Sen, Arko, et al.
Publicado: (2022)

Prognostic Gene Discovery in Glioblastoma Patients using Deep Learning
por: Wong, Kelvin K., et al.
Publicado: (2019)

Identification of glioblastoma gene prognosis modules based on weighted gene co-expression network analysis
por: Xu, Pengfei, et al.
Publicado: (2018)

Named Data Networking for Genomics Data Management and Integrated Workflows
por: Ogle, Cameron, et al.
Publicado: (2021)

Discovery of Novel Human Gene Regulatory Modules from Gene Co-expression and Promoter Motif Analysis
por: Ma, Shisong, et al.
Publicado: (2017)

Growing and cultivating the forest genomics database, TreeGenes
por: Falk, Taylor, et al.
Publicado: (2019)

Growing and cultivating the forest genomics database, TreeGenes
por: Falk, Taylor, et al.
Publicado: (2018)

Identification of key modules and hub genes in glioblastoma multiforme based on co‐expression network analysis
por: Li, Chun, et al.
Publicado: (2021)

Dissecting Prognosis Modules and Biomarkers in Glioblastoma Based on Weighted Gene Co-Expression Network Analysis
por: Cao, Fang, et al.
Publicado: (2021)

Gene expression profiling to predict recurrence of advanced squamous cell carcinoma of the tongue: discovery and external validation
por: Enokida, Tomohiro, et al.
Publicado: (2017)

A genetically anchored physical framework for Theobroma cacao cv. Matina 1-6
por: Saski, Christopher A, et al.
Publicado: (2011)

Identification of key genes involved in the recurrence of glioblastoma multiforme using weighted gene co-expression network analysis and differential expression analysis
por: Ren, Peng, et al.
Publicado: (2021)

EdgeScaping: Mapping the spatial distribution of pairwise gene expression intensities
por: Husain, Benafsh, et al.
Publicado: (2019)

A comparison of base running and sliding techniques in collegiate baseball with implications for sliding into first base
por: Ficklin, Travis, et al.
Publicado: (2016)

Discovery of LAMP-2A as potential biomarkers for glioblastoma development by modulating apoptosis through N-CoR degradation
por: Wang, Yongjie, et al.
Publicado: (2021)

Prognostic Prediction Model for Glioblastoma: A Metabolic Gene Signature and Independent External Validation
por: Lei, Chuxiang, et al.
Publicado: (2021)

Integrative analysis of novel hypomethylation and gene expression signatures in glioblastomas
por: Yin, Anan, et al.
Publicado: (2017)

Sequencing of a QTL-rich region of the Theobroma cacao genome using pooled BACs and the identification of trait specific candidate genes
por: Feltus, Frank A, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_tck6dvg887qc2a2qneub033v3u