APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells

A key feature of prostate cancer progression is the induction and activation of survival proteins, including the Inhibitor of Apoptosis (IAP) family member survivin. Apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1) is a multifunctional protein that is essential in activating...

Descripción completa

Detalles Bibliográficos
Autores principales: McIlwain, David W., Fishel, Melissa L., Boos, Alexander, Kelley, Mark R., Jerde, Travis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834255/
https://www.ncbi.nlm.nih.gov/pubmed/29541389
http://dx.doi.org/10.18632/oncotarget.23493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834255/
https://www.ncbi.nlm.nih.gov/pubmed/29541389
http://dx.doi.org/10.18632/oncotarget.23493

Ejemplares similares