Selective targeting of collagen IV in the cancer cell microenvironment reduces tumor burden

Goodpasture antigen-binding protein (GPBP) is an exportable(1) Ser/Thr kinase that induces collagen IV expansion and has been associated with chemoresistance following epithelial-to-mesenchymal transition (EMT). Here we demonstrate that cancer EMT phenotypes secrete GPBP (mesenchymal GPBP) which dis...

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Detalles Bibliográficos
Autores principales: Revert, Fernando, Revert-Ros, Francisco, Blasco, Raül, Artigot, Aida, López-Pascual, Ernesto, Gozalbo-Rovira, Roberto, Ventura, Ignacio, Gutiérrez-Carbonell, Elain, Roda, Nuria, Ruíz-Sanchis, Daniel, Forteza, Jerónimo, Alcácer, Javier, Pérez-Sastre, Alejandra, Díaz, Ana, Pérez-Payá, Enrique, Sanz-Cervera, Juan F., Saus, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834258/
https://www.ncbi.nlm.nih.gov/pubmed/29541394
http://dx.doi.org/10.18632/oncotarget.24280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834258/
https://www.ncbi.nlm.nih.gov/pubmed/29541394
http://dx.doi.org/10.18632/oncotarget.24280

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