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Cauda equina syndrome secondary to leptomeningeal metastases from recurrent primary peritoneal carcinoma

The patient is a 42-year-old woman with metastatic primary peritoneal carcinoma and known brain metastases, who subsequently developed cauda equina syndrome after presenting with ataxia, lower extremity weakness, and bowel and bladder incontinence secondary to leptomeningeal metastasis after treatme...

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Autores principales: Zhou, Zhen Ni, Canon, Chelsea, Matrai, Cathleen, Chapman-Davis, Eloise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834310/
https://www.ncbi.nlm.nih.gov/pubmed/29515655
http://dx.doi.org/10.3332/ecancer.2018.814
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author Zhou, Zhen Ni
Canon, Chelsea
Matrai, Cathleen
Chapman-Davis, Eloise
author_facet Zhou, Zhen Ni
Canon, Chelsea
Matrai, Cathleen
Chapman-Davis, Eloise
author_sort Zhou, Zhen Ni
collection PubMed
description The patient is a 42-year-old woman with metastatic primary peritoneal carcinoma and known brain metastases, who subsequently developed cauda equina syndrome after presenting with ataxia, lower extremity weakness, and bowel and bladder incontinence secondary to leptomeningeal metastasis after treatment with neoadjuvant chemotherapy, surgical debulking, and adjuvant chemotherapy. Metastases to the central nervous system (CNS) and leptomeninges are rare events in epithelial ovarian and primary peritoneal carcinomas as these tumours do not have a predilection for the CNS. Cauda equina syndrome is often characterised by gait disturbances, bowel and bladder dysfunction, saddle anaesthesia, and lower extremity muscle weakness. In patients with known metastatic gynaecologic carcinomas presenting with nonspecific neurologic symptoms, cauda equina syndrome should remain high in the differential diagnosis.
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spelling pubmed-58343102018-03-07 Cauda equina syndrome secondary to leptomeningeal metastases from recurrent primary peritoneal carcinoma Zhou, Zhen Ni Canon, Chelsea Matrai, Cathleen Chapman-Davis, Eloise Ecancermedicalscience Case Report The patient is a 42-year-old woman with metastatic primary peritoneal carcinoma and known brain metastases, who subsequently developed cauda equina syndrome after presenting with ataxia, lower extremity weakness, and bowel and bladder incontinence secondary to leptomeningeal metastasis after treatment with neoadjuvant chemotherapy, surgical debulking, and adjuvant chemotherapy. Metastases to the central nervous system (CNS) and leptomeninges are rare events in epithelial ovarian and primary peritoneal carcinomas as these tumours do not have a predilection for the CNS. Cauda equina syndrome is often characterised by gait disturbances, bowel and bladder dysfunction, saddle anaesthesia, and lower extremity muscle weakness. In patients with known metastatic gynaecologic carcinomas presenting with nonspecific neurologic symptoms, cauda equina syndrome should remain high in the differential diagnosis. Cancer Intelligence 2018-02-26 /pmc/articles/PMC5834310/ /pubmed/29515655 http://dx.doi.org/10.3332/ecancer.2018.814 Text en © the authors; licensee ecancermedicalscience. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Zhou, Zhen Ni
Canon, Chelsea
Matrai, Cathleen
Chapman-Davis, Eloise
Cauda equina syndrome secondary to leptomeningeal metastases from recurrent primary peritoneal carcinoma
title Cauda equina syndrome secondary to leptomeningeal metastases from recurrent primary peritoneal carcinoma
title_full Cauda equina syndrome secondary to leptomeningeal metastases from recurrent primary peritoneal carcinoma
title_fullStr Cauda equina syndrome secondary to leptomeningeal metastases from recurrent primary peritoneal carcinoma
title_full_unstemmed Cauda equina syndrome secondary to leptomeningeal metastases from recurrent primary peritoneal carcinoma
title_short Cauda equina syndrome secondary to leptomeningeal metastases from recurrent primary peritoneal carcinoma
title_sort cauda equina syndrome secondary to leptomeningeal metastases from recurrent primary peritoneal carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834310/
https://www.ncbi.nlm.nih.gov/pubmed/29515655
http://dx.doi.org/10.3332/ecancer.2018.814
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