Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns

Immunoglobulin G (IgG), a glycoprotein secreted by plasma B-cells, plays a major role in the human adaptive immune response and are associated with a wide range of diseases. Glycosylation of the Fc binding region of IgGs, responsible for the antibody’s effector function, is essential for prompting a...

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Detalles Bibliográficos
Autores principales: Wahl, Annika, van den Akker, Erik, Klaric, Lucija, Štambuk, Jerko, Benedetti, Elisa, Plomp, Rosina, Razdorov, Genadij, Trbojević-Akmačić, Irena, Deelen, Joris, van Heemst, Diana, Slagboom, P. Eline, Vučković, Frano, Grallert, Harald, Krumsiek, Jan, Strauch, Konstantin, Peters, Annette, Meitinger, Thomas, Hayward, Caroline, Wuhrer, Manfred, Beekman, Marian, Lauc, Gordan, Gieger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834439/
https://www.ncbi.nlm.nih.gov/pubmed/29535710
http://dx.doi.org/10.3389/fimmu.2018.00277

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