The effects of angiotensin receptor neprilysin inhibition by sacubitril/valsartan on adipose tissue transcriptome and protein expression in obese hypertensive patients

Increased activation of the renin-angiotensin system is involved in the onset and progression of cardiometabolic diseases, while natriuretic peptides (NP) may exert protective effects. We have recently demonstrated that sacubitril/valsartan (LCZ696), a first-in-class angiotensin receptor neprilysin...

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Detalles Bibliográficos
Autores principales: Stinkens, R., van der Kolk, B. W., Jordan, J., Jax, T., Engeli, S., Heise, T., Jocken, J. W., May, M., Schindler, C., Havekes, B., Schaper, N., Albrecht, D., Kaiser, S., Hartmann, N., Letzkus, M., Langenickel, T. H., Goossens, G. H., Blaak, E. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834447/
https://www.ncbi.nlm.nih.gov/pubmed/29500454
http://dx.doi.org/10.1038/s41598-018-22194-z

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