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Item-level analyses reveal genetic heterogeneity in neuroticism
Genome-wide association studies (GWAS) of psychological traits are generally conducted on (dichotomized) sums of items or symptoms (e.g., case-control status), and not on the individual items or symptoms themselves. We conduct large-scale GWAS on 12 neuroticism items and observe notable and replicab...
Autores principales: | Nagel, Mats, Watanabe, Kyoko, Stringer, Sven, Posthuma, Danielle, van der Sluis, Sophie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834468/ https://www.ncbi.nlm.nih.gov/pubmed/29500382 http://dx.doi.org/10.1038/s41467-018-03242-8 |
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