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CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1

Na(+)-coupled acid–base transporters play essential roles in human biology. Their dysfunction has been linked to cancer, heart, and brain disease. High-resolution structures of mammalian Na(+)-coupled acid–base transporters are not available. The sodium-bicarbonate cotransporter NBCe1 functions in m...

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Detalles Bibliográficos
Autores principales: Huynh, Kevin W., Jiang, Jiansen, Abuladze, Natalia, Tsirulnikov, Kirill, Kao, Liyo, Shao, Xuesi, Newman, Debra, Azimov, Rustam, Pushkin, Alexander, Zhou, Z. Hong, Kurtz, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834491/
https://www.ncbi.nlm.nih.gov/pubmed/29500354
http://dx.doi.org/10.1038/s41467-018-03271-3

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