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CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1
Na(+)-coupled acid–base transporters play essential roles in human biology. Their dysfunction has been linked to cancer, heart, and brain disease. High-resolution structures of mammalian Na(+)-coupled acid–base transporters are not available. The sodium-bicarbonate cotransporter NBCe1 functions in m...
Autores principales: | Huynh, Kevin W., Jiang, Jiansen, Abuladze, Natalia, Tsirulnikov, Kirill, Kao, Liyo, Shao, Xuesi, Newman, Debra, Azimov, Rustam, Pushkin, Alexander, Zhou, Z. Hong, Kurtz, Ira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834491/ https://www.ncbi.nlm.nih.gov/pubmed/29500354 http://dx.doi.org/10.1038/s41467-018-03271-3 |
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