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Central s-resistin deficiency ameliorates hypothalamic inflammation and increases whole body insulin sensitivity
S-resistin, a non-secretable resistin isoform, acts as an intracrine factor that regulates adipocyte maduration, inflammatory and insulin response in 3T3-L1 cells. However, its intracellular function in vivo is still unknown. In this study, we analyze the central role of s-resistin, decreasing its h...
Autores principales: | Rodríguez, María, Pintado, Cristina, Moltó, Eduardo, Gallardo, Nilda, Fernández-Martos, Carmen M., López, Virginia, Andrés, Antonio, Arribas, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834531/ https://www.ncbi.nlm.nih.gov/pubmed/29500410 http://dx.doi.org/10.1038/s41598-018-22255-3 |
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