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A Mathematical Model of the Phosphoinositide Pathway

Phosphoinositides are signalling lipids that constitute a complex network regulating many cellular processes. We propose a computational model that accounts for all species of phosphoinositides in the plasma membrane of mammalian cells. The model replicates the steady-state of the pathway and most k...

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Detalles Bibliográficos
Autores principales:	Olivença, Daniel V., Uliyakina, Inna, Fonseca, Luis L., Amaral, Margarida D., Voit, Eberhard O., Pinto, Francisco R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834545/ https://www.ncbi.nlm.nih.gov/pubmed/29500467 http://dx.doi.org/10.1038/s41598-018-22226-8

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