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Characterisation of fibrosis in chemically-induced rat mammary carcinomas using multi-modal endogenous contrast MRI on a 1.5T clinical platform

OBJECTIVES: To determine the ability of multi-parametric, endogenous contrast MRI to detect and quantify fibrosis in a chemically-induced rat model of mammary carcinoma. METHODS: Female Sprague-Dawley rats (n=18) were administered with N-methyl-N-nitrosourea; resulting mammary carcinomas underwent n...

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Detalles Bibliográficos
Autores principales: Jerome, Neil P., Boult, Jessica K. R., Orton, Matthew R., d’Arcy, James A., Nerurkar, Ashutosh, Leach, Martin O., Koh, Dow-Mu, Collins, David J., Robinson, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834566/
https://www.ncbi.nlm.nih.gov/pubmed/29038934
http://dx.doi.org/10.1007/s00330-017-5083-6