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Gravity and neuronal adaptation, in vitro and in vivo—from neuronal cells up to neuromuscular responses: a first model

For decades it has been shown that acute changes in gravity have an effect on neuronal systems of human and animals on different levels, from the molecular level to the whole nervous system. The functional properties and gravity-dependent adaptations of these system levels have been investigated wit...

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Autores principales: Kohn, Florian P. M., Ritzmann, Ramona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834568/
https://www.ncbi.nlm.nih.gov/pubmed/28656475
http://dx.doi.org/10.1007/s00249-017-1233-7
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author Kohn, Florian P. M.
Ritzmann, Ramona
author_facet Kohn, Florian P. M.
Ritzmann, Ramona
author_sort Kohn, Florian P. M.
collection PubMed
description For decades it has been shown that acute changes in gravity have an effect on neuronal systems of human and animals on different levels, from the molecular level to the whole nervous system. The functional properties and gravity-dependent adaptations of these system levels have been investigated with no or barely any interconnection. This review summarizes the gravity-dependent adaptation processes in human and animal organisms from the in vitro cellular level with its biophysical properties to the in vivo motor responses and underlying sensorimotor functions of human subjects. Subsequently, a first model for short-term adaptation of neuronal transmission is presented and discussed for the first time, which integrates the responses of the different levels of organization to changes in gravity.
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spelling pubmed-58345682018-03-09 Gravity and neuronal adaptation, in vitro and in vivo—from neuronal cells up to neuromuscular responses: a first model Kohn, Florian P. M. Ritzmann, Ramona Eur Biophys J Review For decades it has been shown that acute changes in gravity have an effect on neuronal systems of human and animals on different levels, from the molecular level to the whole nervous system. The functional properties and gravity-dependent adaptations of these system levels have been investigated with no or barely any interconnection. This review summarizes the gravity-dependent adaptation processes in human and animal organisms from the in vitro cellular level with its biophysical properties to the in vivo motor responses and underlying sensorimotor functions of human subjects. Subsequently, a first model for short-term adaptation of neuronal transmission is presented and discussed for the first time, which integrates the responses of the different levels of organization to changes in gravity. Springer International Publishing 2017-06-27 2018 /pmc/articles/PMC5834568/ /pubmed/28656475 http://dx.doi.org/10.1007/s00249-017-1233-7 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review
Kohn, Florian P. M.
Ritzmann, Ramona
Gravity and neuronal adaptation, in vitro and in vivo—from neuronal cells up to neuromuscular responses: a first model
title Gravity and neuronal adaptation, in vitro and in vivo—from neuronal cells up to neuromuscular responses: a first model
title_full Gravity and neuronal adaptation, in vitro and in vivo—from neuronal cells up to neuromuscular responses: a first model
title_fullStr Gravity and neuronal adaptation, in vitro and in vivo—from neuronal cells up to neuromuscular responses: a first model
title_full_unstemmed Gravity and neuronal adaptation, in vitro and in vivo—from neuronal cells up to neuromuscular responses: a first model
title_short Gravity and neuronal adaptation, in vitro and in vivo—from neuronal cells up to neuromuscular responses: a first model
title_sort gravity and neuronal adaptation, in vitro and in vivo—from neuronal cells up to neuromuscular responses: a first model
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834568/
https://www.ncbi.nlm.nih.gov/pubmed/28656475
http://dx.doi.org/10.1007/s00249-017-1233-7
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