Correction of Huntington’s Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model

Huntington’s disease (HD) is a monogenic disorder, caused by mutations in the HTT gene which result in expansion of CAG triplets. The product of the mutated gene is misfolded huntingtin protein that forms aggregates leading to impairment of neuronal function, neurodegeneration, motor abnormalities a...

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Detalles Bibliográficos
Autores principales: Pierzynowska, Karolina, Gaffke, Lidia, Hać, Aleksandra, Mantej, Jagoda, Niedziałek, Natalia, Brokowska, Joanna, Węgrzyn, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834590/
https://www.ncbi.nlm.nih.gov/pubmed/29435951
http://dx.doi.org/10.1007/s12017-018-8482-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834590/
https://www.ncbi.nlm.nih.gov/pubmed/29435951
http://dx.doi.org/10.1007/s12017-018-8482-1

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