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Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning
Oligodendrocytes produce myelin for rapid transmission and saltatory conduction of action potentials in the vertebrate central nervous system. Activation of the myelination program requires several transcription factors including Sox10, Olig2, and Nkx2.2. Functional interactions among them are poorl...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834605/ https://www.ncbi.nlm.nih.gov/pubmed/29500351 http://dx.doi.org/10.1038/s41467-018-03336-3 |