gDNA qPCR is statistically more reliable than mRNA analysis in detecting leukemic cells to monitor CML

Chronic Myeloid Leukemia (CML) is a stem cell cancer that arises when t(9;22) translocation occurs in a hematopoietic stem cells. This event results in the expression of the BCR-ABL1 fusion gene, which codes for a constitutively active tyrosine kinase that is responsible for the transformation of a...

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Detalles Bibliográficos
Autores principales: Rainero, Alessia, Angaroni, Fabrizio, D’Avila, Francesca, Conti, Andrea, Pirrone, Cristina, Micheloni, Giovanni, Tararà, Lucia, Millefanti, Giorgia, Maserati, Emanuela, Valli, Roberto, Spinelli, Orietta, Buklijas, Ksenija, Michelato, Anna, Casalone, Rosario, Barlassina, Cristina, Barcella, Matteo, Sirchia, Silvia, Piscitelli, Eleonora, Caccia, Massimo, Porta, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834620/
https://www.ncbi.nlm.nih.gov/pubmed/29500381
http://dx.doi.org/10.1038/s41419-018-0387-2

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