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Epigenetic modifiers promote mitochondrial biogenesis and oxidative metabolism leading to enhanced differentiation of neuroprogenitor cells

During neural development, epigenetic modulation of chromatin acetylation is part of a dynamic, sequential and critical process to steer the fate of multipotent neural progenitors toward a specific lineage. Pan-HDAC inhibitors (HDCis) trigger neuronal differentiation by generating an “acetylation” s...

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Detalles Bibliográficos
Autores principales:	Uittenbogaard, Martine, Brantner, Christine A., Chiaramello, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834638/ https://www.ncbi.nlm.nih.gov/pubmed/29500414 http://dx.doi.org/10.1038/s41419-018-0396-1

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