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Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain

DNA methylation is an important epigenetic modification involved in gene regulation and transposable element silencing. Changes in DNA methylation can be heritable and, thus, can lead to the formation of stable epialleles. A well-characterized example of a stable epiallele in plants is fwa, which co...

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Detalles Bibliográficos
Autores principales:	Gallego-Bartolomé, Javier, Gardiner, Jason, Liu, Wanlu, Papikian, Ashot, Ghoshal, Basudev, Kuo, Hsuan Yu, Zhao, Jenny Miao-Chi, Segal, David J., Jacobsen, Steven E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2018
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834696/ https://www.ncbi.nlm.nih.gov/pubmed/29444862 http://dx.doi.org/10.1073/pnas.1716945115

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