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2‐anilino‐4‐amino‐5‐aroylthiazole‐type compound AS7128 inhibits lung cancer growth through decreased iASPP and p53 interaction
Lung cancer is the leading cause of cancer‐related death worldwide. Thus, developing novel therapeutic agents has become critical for lung cancer treatment. In this study, compound AS7128 was selected from a 2‐million entry chemical library screening and identified as a candidate drug against non‐sm...
Autores principales: | Cheng, Hao‐Wei, Chein, Rong‐Jie, Cheng, Ting‐Jen, Wu, Pei‐Shan, Wu, Hsin‐Yi, Hung, Pei‐Fang, Wang, Chia‐Jen, Hsu, Yuan‐Ling, Wong, Jau‐Min, Yuan, Ang, Wong, Chi‐Huey, Yang, Pan‐Chyr, Pan, Szu‐Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834782/ https://www.ncbi.nlm.nih.gov/pubmed/29285847 http://dx.doi.org/10.1111/cas.13489 |
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