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Csf1r-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System
CSF1 is the primary growth factor controlling macrophage numbers, but whether expression of the CSF1 receptor differs between discrete populations of mononuclear phagocytes remains unclear. We have generated a Csf1r-mApple transgenic fluorescent reporter mouse that, in combination with lineage traci...
Autores principales: | Hawley, Catherine A., Rojo, Rocio, Raper, Anna, Sauter, Kristin A., Lisowski, Zofia M., Grabert, Kathleen, Bain, Calum C., Davis, Gemma M., Louwe, Pieter A., Ostrowski, Michael C., Hume, David A., Pridans, Clare, Jenkins, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834790/ https://www.ncbi.nlm.nih.gov/pubmed/29440354 http://dx.doi.org/10.4049/jimmunol.1701488 |
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