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Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions

BACKGROUND: The efficacy of antibiotics against M. tuberculosis has been shown to be influenced by experimental media conditions. Investigations of M. tuberculosis growth in physiological conditions have described an environment that is different from common in vitro media. Thus, elucidating the int...

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Detalles Bibliográficos
Autores principales:	Kavvas, Erol S., Seif, Yara, Yurkovich, James T., Norsigian, Charles, Poudel, Saugat, Greenwald, William W., Ghatak, Sankha, Palsson, Bernhard O., Monk, Jonathan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834885/ https://www.ncbi.nlm.nih.gov/pubmed/29499714 http://dx.doi.org/10.1186/s12918-018-0557-y

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