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Vascular Endothelial Cell-Specific Connective Tissue Growth Factor (CTGF) Is Necessary for Development of Chronic Hypoxia-Induced Pulmonary Hypertension

Chronic hypoxia frequently complicates the care of patients with interstitial lung disease, contributing to the development of pulmonary hypertension (PH), and premature death. Connective tissue growth factor (CTGF), a matricellular protein of the Cyr61/CTGF/Nov (CCN) family, is known to exacerbate...

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Detalles Bibliográficos
Autores principales:	Pi, Liya, Fu, Chunhua, Lu, Yuanquing, Zhou, Junmei, Jorgensen, Marda, Shenoy, Vinayak, Lipson, Kenneth E., Scott, Edward W., Bryant, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835098/ https://www.ncbi.nlm.nih.gov/pubmed/29535639 http://dx.doi.org/10.3389/fphys.2018.00138

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