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Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells

Immune checkpoint inhibition has been shown to successfully reactivate endogenous T cell responses directed against tumor-associated antigens, resulting in significantly prolonged overall survival in patients with various tumor entities. For malignancies with low endogenous immune responses, this ap...

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Detalles Bibliográficos
Autores principales:	Lichtenegger, Felix S., Rothe, Maurine, Schnorfeil, Frauke M., Deiser, Katrin, Krupka, Christina, Augsberger, Christian, Schlüter, Miriam, Neitz, Julia, Subklewe, Marion
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835137/ https://www.ncbi.nlm.nih.gov/pubmed/29535740 http://dx.doi.org/10.3389/fimmu.2018.00385

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