Metabolic Heterogeneity Evidenced by MRS among Patient-Derived Glioblastoma Multiforme Stem-Like Cells Accounts for Cell Clustering and Different Responses to Drugs

Clustering of patient-derived glioma stem-like cells (GSCs) through unsupervised analysis of metabolites detected by magnetic resonance spectroscopy (MRS) evidenced three subgroups, namely clusters 1a and 1b, with high intergroup similarity and neural fingerprints, and cluster 2, with a metabolism t...

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Detalles Bibliográficos
Autores principales: Grande, Sveva, Palma, Alessandra, Ricci-Vitiani, Lucia, Luciani, Anna Maria, Buccarelli, Mariachiara, Biffoni, Mauro, Molinari, Agnese, Calcabrini, Annarica, D'Amore, Emanuela, Guidoni, Laura, Pallini, Roberto, Viti, Vincenza, Rosi, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835274/
https://www.ncbi.nlm.nih.gov/pubmed/29531533
http://dx.doi.org/10.1155/2018/3292704

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