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A Challenging Case of Acute Mercury Toxicity

BACKGROUND: Mercury exists in multiple forms: elemental, organic, and inorganic. Its toxic manifestations depend on the type and magnitude of exposure. The role of colonoscopic decompression in acute mercury toxicity is still unclear. We present a case of acute elemental mercury toxicity secondary t...

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Autores principales: Nayfeh, Ali, Kassim, Thamer, Addasi, Noor, Alghoula, Faysal, Holewinski, Christopher, Depew, Zachary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835301/
https://www.ncbi.nlm.nih.gov/pubmed/29559996
http://dx.doi.org/10.1155/2018/1010678
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author Nayfeh, Ali
Kassim, Thamer
Addasi, Noor
Alghoula, Faysal
Holewinski, Christopher
Depew, Zachary
author_facet Nayfeh, Ali
Kassim, Thamer
Addasi, Noor
Alghoula, Faysal
Holewinski, Christopher
Depew, Zachary
author_sort Nayfeh, Ali
collection PubMed
description BACKGROUND: Mercury exists in multiple forms: elemental, organic, and inorganic. Its toxic manifestations depend on the type and magnitude of exposure. The role of colonoscopic decompression in acute mercury toxicity is still unclear. We present a case of acute elemental mercury toxicity secondary to mercury ingestion, which markedly improved with colonoscopic decompression. CLINICAL CASE: A 54-year-old male presented to the ED five days after ingesting five ounces (148 cubic centimeters) of elemental mercury. Examination was only significant for a distended abdomen. Labs showed elevated serum and urine mercury levels. An abdominal radiograph showed radiopaque material throughout the colon. Succimer and laxatives were initiated. The patient had recurrent bowel movements, and serial radiographs showed interval decrease of mercury in the descending colon with interval increase in the cecum and ascending colon. Colonoscopic decompression was done successfully. The colon was evacuated, and a repeat radiograph showed decreased hyperdense material in the colon. Three months later, a repeat radiograph showed no hyperdense material in the colon. CONCLUSION: Ingested elemental mercury can be retained in the colon. Although there are no established guidelines for colonoscopic decompression, our patient showed significant improvement. We believe further studies on this subject are needed to guide management practices.
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spelling pubmed-58353012018-03-20 A Challenging Case of Acute Mercury Toxicity Nayfeh, Ali Kassim, Thamer Addasi, Noor Alghoula, Faysal Holewinski, Christopher Depew, Zachary Case Rep Med Case Report BACKGROUND: Mercury exists in multiple forms: elemental, organic, and inorganic. Its toxic manifestations depend on the type and magnitude of exposure. The role of colonoscopic decompression in acute mercury toxicity is still unclear. We present a case of acute elemental mercury toxicity secondary to mercury ingestion, which markedly improved with colonoscopic decompression. CLINICAL CASE: A 54-year-old male presented to the ED five days after ingesting five ounces (148 cubic centimeters) of elemental mercury. Examination was only significant for a distended abdomen. Labs showed elevated serum and urine mercury levels. An abdominal radiograph showed radiopaque material throughout the colon. Succimer and laxatives were initiated. The patient had recurrent bowel movements, and serial radiographs showed interval decrease of mercury in the descending colon with interval increase in the cecum and ascending colon. Colonoscopic decompression was done successfully. The colon was evacuated, and a repeat radiograph showed decreased hyperdense material in the colon. Three months later, a repeat radiograph showed no hyperdense material in the colon. CONCLUSION: Ingested elemental mercury can be retained in the colon. Although there are no established guidelines for colonoscopic decompression, our patient showed significant improvement. We believe further studies on this subject are needed to guide management practices. Hindawi 2018-02-18 /pmc/articles/PMC5835301/ /pubmed/29559996 http://dx.doi.org/10.1155/2018/1010678 Text en Copyright © 2018 Ali Nayfeh et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nayfeh, Ali
Kassim, Thamer
Addasi, Noor
Alghoula, Faysal
Holewinski, Christopher
Depew, Zachary
A Challenging Case of Acute Mercury Toxicity
title A Challenging Case of Acute Mercury Toxicity
title_full A Challenging Case of Acute Mercury Toxicity
title_fullStr A Challenging Case of Acute Mercury Toxicity
title_full_unstemmed A Challenging Case of Acute Mercury Toxicity
title_short A Challenging Case of Acute Mercury Toxicity
title_sort challenging case of acute mercury toxicity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835301/
https://www.ncbi.nlm.nih.gov/pubmed/29559996
http://dx.doi.org/10.1155/2018/1010678
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