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The MEK1/2-ERK Pathway Inhibits Type I IFN Production in Plasmacytoid Dendritic Cells

Recent studies have reported that the crosslinking of regulatory receptors (RRs), such as blood dendritic cell antigen 2 (BDCA-2) (CD303) or ILT7 (CD85g), of plasmacytoid dendritic cells (pDCs) efficiently suppresses the production of type I interferons (IFN-I, α/β/ω) and other cytokines in response...

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Detalles Bibliográficos
Autores principales:	Janovec, Vaclav, Aouar, Besma, Font-Haro, Albert, Hofman, Tomas, Trejbalova, Katerina, Weber, Jan, Chaperot, Laurence, Plumas, Joel, Olive, Daniel, Dubreuil, Patrice, Nunès, Jacques A., Stranska, Ruzena, Hirsch, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835309/ https://www.ncbi.nlm.nih.gov/pubmed/29535732 http://dx.doi.org/10.3389/fimmu.2018.00364

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