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Tetrathiomolybdate Treatment Leads to the Suppression of Inflammatory Responses through the TRAF6/NFκB Pathway in LPS-Stimulated BV-2 Microglia
Although the positive relationship between copper and Alzheimer's disease (AD) was reported by a lot of epidemiological data, the mechanism is not completely known. Copper is a redox metal and serves as a mediator of inflammation. Because the homeostasis of copper is altered in Aβ precursor pro...
Autores principales: | Wang, Zhuo, Zhang, Ya-Hong, Guo, Chuang, Gao, Hui-Ling, Zhong, Man-Li, Huang, Ting-Ting, Liu, Na-Na, Guo, Rui-Fang, Lan, Tian, Zhang, Wei, Wang, Zhan-You, Zhao, Pu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835334/ https://www.ncbi.nlm.nih.gov/pubmed/29535623 http://dx.doi.org/10.3389/fnagi.2018.00009 |
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