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The effect of xanthine oxidase and hypoxanthine on the permeability of red cells from patients with sickle cell anemia

Red cells from patients with sickle cell anemia (SCA) are under greater oxidative challenge than those from normal individuals. We postulated that oxidants generated by xanthine oxidase (XO) and hypoxanthine (HO) contribute to the pathogenesis of SCA through altering solute permeability. Sickling, a...

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Detalles Bibliográficos
Autores principales:	Al Balushi, Halima W. M., Rees, David C., Brewin, John N., Hannemann, Anke, Gibson, John S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835498/ https://www.ncbi.nlm.nih.gov/pubmed/29504282 http://dx.doi.org/10.14814/phy2.13626

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