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PERK Pathway Activation Promotes Intracerebral Hemorrhage Induced Secondary Brain Injury by Inducing Neuronal Apoptosis Both in Vivo and in Vitro
The protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) signaling pathway was reported to exert an important role in neuronal apoptosis. The present study was designed to investigate the roles of the PERK signaling pathway in the secondary brain injury (SBI) induced by intracerebral hemo...
Autores principales: | Meng, Chengjie, Zhang, Juyi, Dang, Baoqi, Li, Haiying, Shen, Haitao, Li, Xiang, Wang, Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835756/ https://www.ncbi.nlm.nih.gov/pubmed/29541018 http://dx.doi.org/10.3389/fnins.2018.00111 |
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