The Effect of TNF-α on Regulatory T Cell Function in Graft-versus-Host Disease

FoxP3(+) regulatory T cells (Tregs) are a subset of CD4(+) T cells that can suppress proliferation and effector functions of T cells, B cells, NK cells, and antigen-presenting cells. Treg deficiency causes dramatic immunologic disease in both animal models and humans. As they are capable to suppress...

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Detalles Bibliográficos
Autores principales: Mancusi, Antonella, Piccinelli, Sara, Velardi, Andrea, Pierini, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835761/
https://www.ncbi.nlm.nih.gov/pubmed/29541073
http://dx.doi.org/10.3389/fimmu.2018.00356

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