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UPR(mt) regulation and output: a stress response mediated by mitochondrial-nuclear communication
The mitochondrial network is not only required for the production of energy, essential cofactors and amino acids, but also serves as a signaling hub for innate immune and apoptotic pathways. Multiple mechanisms have evolved to identify and combat mitochondrial dysfunction to maintain the health of t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835775/ https://www.ncbi.nlm.nih.gov/pubmed/29424373 http://dx.doi.org/10.1038/cr.2018.16 |