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m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration

The function of mitochondria depends on ubiquitously expressed and evolutionary conserved m-AAA proteases in the inner membrane. These ATP-dependent peptidases form hexameric complexes built up of homologous subunits. AFG3L2 subunits assemble either into homo-oligomeric isoenzymes or with SPG7 (para...

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Detalles Bibliográficos
Autores principales:	Patron, Maria, Sprenger, Hans-Georg, Langer, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835776/ https://www.ncbi.nlm.nih.gov/pubmed/29451229 http://dx.doi.org/10.1038/cr.2018.17

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