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Indocyanine green-incorporating nanoparticles for cancer theranostics

Indocyanine green (ICG) is a near-infrared dye that has been used in the clinic for retinal angiography, and defining cardiovascular and liver function for over 50 years. Recently, there has been an increasing interest in the incorporation of ICG into nanoparticles (NPs) for cancer theranostic appli...

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Autores principales: Wang, Haolu, Li, Xinxing, Tse, Brian Wan-Chi, Yang, Haotian, Thorling, Camilla A., Liu, Yuxin, Touraud, Margaux, Chouane, Jean Batiste, Liu, Xin, Roberts, Michael S., Liang, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835932/
https://www.ncbi.nlm.nih.gov/pubmed/29507616
http://dx.doi.org/10.7150/thno.22872
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author Wang, Haolu
Li, Xinxing
Tse, Brian Wan-Chi
Yang, Haotian
Thorling, Camilla A.
Liu, Yuxin
Touraud, Margaux
Chouane, Jean Batiste
Liu, Xin
Roberts, Michael S.
Liang, Xiaowen
author_facet Wang, Haolu
Li, Xinxing
Tse, Brian Wan-Chi
Yang, Haotian
Thorling, Camilla A.
Liu, Yuxin
Touraud, Margaux
Chouane, Jean Batiste
Liu, Xin
Roberts, Michael S.
Liang, Xiaowen
author_sort Wang, Haolu
collection PubMed
description Indocyanine green (ICG) is a near-infrared dye that has been used in the clinic for retinal angiography, and defining cardiovascular and liver function for over 50 years. Recently, there has been an increasing interest in the incorporation of ICG into nanoparticles (NPs) for cancer theranostic applications. Various types of ICG-incorporated NPs have been developed and strategically functionalised to embrace multiple imaging and therapeutic techniques for cancer diagnosis and treatment. This review systematically summaries the biodistribution of various types of ICG-incorporated NPs for the first time, and discusses the principles, opportunities, limitations, and application of ICG-incorporated NPs for cancer theranostics. We believe that ICG-incorporated NPs would be a promising multifunctional theranostic platform in oncology and facilitate significant advancements in this research-active area.
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spelling pubmed-58359322018-03-05 Indocyanine green-incorporating nanoparticles for cancer theranostics Wang, Haolu Li, Xinxing Tse, Brian Wan-Chi Yang, Haotian Thorling, Camilla A. Liu, Yuxin Touraud, Margaux Chouane, Jean Batiste Liu, Xin Roberts, Michael S. Liang, Xiaowen Theranostics Review Indocyanine green (ICG) is a near-infrared dye that has been used in the clinic for retinal angiography, and defining cardiovascular and liver function for over 50 years. Recently, there has been an increasing interest in the incorporation of ICG into nanoparticles (NPs) for cancer theranostic applications. Various types of ICG-incorporated NPs have been developed and strategically functionalised to embrace multiple imaging and therapeutic techniques for cancer diagnosis and treatment. This review systematically summaries the biodistribution of various types of ICG-incorporated NPs for the first time, and discusses the principles, opportunities, limitations, and application of ICG-incorporated NPs for cancer theranostics. We believe that ICG-incorporated NPs would be a promising multifunctional theranostic platform in oncology and facilitate significant advancements in this research-active area. Ivyspring International Publisher 2018-02-02 /pmc/articles/PMC5835932/ /pubmed/29507616 http://dx.doi.org/10.7150/thno.22872 Text en © Ivyspring International Publisher This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Wang, Haolu
Li, Xinxing
Tse, Brian Wan-Chi
Yang, Haotian
Thorling, Camilla A.
Liu, Yuxin
Touraud, Margaux
Chouane, Jean Batiste
Liu, Xin
Roberts, Michael S.
Liang, Xiaowen
Indocyanine green-incorporating nanoparticles for cancer theranostics
title Indocyanine green-incorporating nanoparticles for cancer theranostics
title_full Indocyanine green-incorporating nanoparticles for cancer theranostics
title_fullStr Indocyanine green-incorporating nanoparticles for cancer theranostics
title_full_unstemmed Indocyanine green-incorporating nanoparticles for cancer theranostics
title_short Indocyanine green-incorporating nanoparticles for cancer theranostics
title_sort indocyanine green-incorporating nanoparticles for cancer theranostics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835932/
https://www.ncbi.nlm.nih.gov/pubmed/29507616
http://dx.doi.org/10.7150/thno.22872
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