Pharmacological Ascorbate Suppresses Growth of Gastric Cancer Cells with GLUT1 Overexpression and Enhances the Efficacy of Oxaliplatin Through Redox Modulation

Rationale: The antitumor activity of high-dose ascorbate has been re-evaluated recently, but the mechanism underlying cell-specific sensitivity to ascorbate has not yet been clarified. Methods: The effects of high-dose ascorbate on gastric cancer were assessed using cancer cell lines with high and l...

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Detalles Bibliográficos
Autores principales: Lu, Yun-Xin, Wu, Qi-Nian, Chen, Dong-liang, Chen, Le-Zong, Wang, Zi-Xian, Ren, Chao, Mo, Hai-yu, Chen, Ya, Sheng, Hui, Wang, Ying-Nan, Wang, Yun, Lu, Jia-Huan, Wang, De-shen, Zeng, Zhao-lei, Wang, Feng, Wang, Feng-Hua, Li, Yu-Hong, Ju, Huai-Qiang, Xu, Rui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835938/
https://www.ncbi.nlm.nih.gov/pubmed/29507622
http://dx.doi.org/10.7150/thno.21745

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