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Desmin- and vimentin-mediated hepatic stellate cell-targeting radiotracer (99m)Tc-GlcNAc-PEI for liver fibrosis imaging with SPECT
Extracellular matrix (ECM) accumulation in liver fibrosis is caused by the activation of hepatic stellate cells (HSCs). The goal of this study was to develop a (99m)Tc-labeled N-acetylglucosamine (GlcNAc) that specifically interacts with desmin and vimentin expressed on activated HSCs to monitor the...
Autores principales: | Zhang, Deliang, Zhuang, Rongqiang, Guo, Zhide, Gao, Mengna, Huang, Lumei, You, Linyi, Zhang, Pu, Li, Jindian, Su, Xinhui, Wu, Hua, Chen, Xiaoyuan, Zhang, Xianzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835940/ https://www.ncbi.nlm.nih.gov/pubmed/29507624 http://dx.doi.org/10.7150/thno.22806 |
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