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Targeting Tumor Hypoxia Using Nanoparticle-engineered CXCR4-overexpressing Adipose-derived Stem Cells

Hypoxia, a hallmark of malignant tumors, often correlates with increasing tumor aggressiveness and poor treatment outcomes. Due to a lack of vasculature, effective drug delivery to hypoxic tumor regions remains challenging. Signaling through the chemokine SDF-1α and its receptor CXCR4 plays a critic...

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Detalles Bibliográficos
Autores principales:	Jiang, Xinyi, Wang, Christine, Fitch, Sergio, Yang, Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835941/ https://www.ncbi.nlm.nih.gov/pubmed/29507625 http://dx.doi.org/10.7150/thno.22736

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